How Bone Loss Happens
Bone is living tissue that is constantly broken down and rebuilt. Most people reach their peak bone mass in early adulthood; after that, bone breakdown gradually outpaces bone formation. When the loss becomes significant, the inner structure of bone turns porous and fragile.
Hormones play a major role. The drop in estrogen at menopause speeds up bone loss, which is why women are affected most often, and low testosterone can weaken bones in men. Bone density that is lower than normal but not yet in the osteoporosis range is called low bone mass, or osteopenia.
Signs of Osteoporosis
Most people have no symptoms until a bone breaks. The first sign is often a fracture of the wrist, hip, or spine after a minor fall. Spinal (vertebral) fractures can cause sudden back pain, but some happen silently and only show up over time as lost height or a stooped posture.
Bone Density Testing and Diagnosis
The U.S. Preventive Services Task Force recommends osteoporosis screening for all women 65 and older and for younger postmenopausal women at increased fracture risk. The Bone Health & Osteoporosis Foundation also advises testing for men 70 and older and for anyone who breaks a bone after age 50.
A hip or spine fracture from minor trauma can indicate osteoporosis even when bone density looks better than expected. Your clinician may also use FRAX, a tool that estimates your 10-year probability of a major fracture, to guide treatment decisions.
Bone density is measured with a DXA (dual-energy X-ray absorptiometry) scan, a quick, low-radiation test of the hip and spine. Results are reported as a T-score:
- -1.0 or above: normal bone density
- Between -1.0 and -2.5: low bone mass (osteopenia)
- -2.5 or below: osteoporosis
Osteoporosis Treatment Options
Calcium and vitamin D are the foundation. The Bone Health & Osteoporosis Foundation recommends 1,200 mg of calcium daily from all sources for women 51 and older and men 71 and older, and 800 to 1,000 IU of vitamin D for most adults 50 and older. Food comes first, with supplements filling any gap.
For people at high fracture risk, medication can strengthen bone and lower the chance of breaking one:
- Bisphosphonates (alendronate, risedronate, ibandronate, zoledronic acid) slow bone breakdown and are taken as weekly or monthly pills or a yearly infusion
- Denosumab, an injection every six months; stopping it without switching to another medicine can cause rapid bone loss and spine fractures, so it should never be stopped without a plan
- Bone-building (anabolic) medicines such as teriparatide, abaloparatide, and romosozumab, often used for very high risk and followed by a medicine that preserves the new bone
- Other options, including raloxifene or menopausal hormone therapy, for selected patients
Bone Health Care With an Endocrinologist at TopInspired.com
We review your DXA report and, when possible, compare scans done on the same machine over time. We estimate your fracture risk and look for secondary causes with labs such as calcium, vitamin D, parathyroid hormone, kidney function, thyroid tests, and testosterone for men when appropriate.
Your endocrinologist then matches treatment to your risk level, health history, and preferences, discusses possible side effects, and plans the long-term sequence, including when a break from bisphosphonates (a drug holiday) may be reasonable. We coordinate with your primary care doctor, dentist, and orthopedic team. Schedule a bone health visit in person or virtually.
Protecting Your Bones Every Day
- Do weight-bearing exercise such as walking, plus muscle-strengthening and balance work like tai chi
- Fall-proof your home with good lighting, secured rugs, and bathroom grab bars
- Get regular vision checks and ask whether any of your medicines cause dizziness or drowsiness
- Avoid smoking and limit alcohol
- Eat enough protein, calcium, and vitamin D, and keep follow-up bone density scans on schedule
When to see a TopInspired endocrinologist
- Your T-score is -2.5 or lower, or you broke a bone in a minor fall after age 50
- You're losing bone or had a fracture despite taking osteoporosis medicine
- You have osteoporosis before menopause, at a younger age, or as a man
- Your calcium, parathyroid hormone, or vitamin D levels are abnormal
- You take long-term steroids or cancer treatments that affect bone
- You have questions about stopping or switching medicines, including denosumab or a bisphosphonate drug holiday
- You have kidney disease or another condition that limits your medication options
Osteoporosis & Bone Health: frequently asked questions
Can osteoporosis be reversed?
Osteoporosis is usually a long-term condition, but treatment can make a real difference. Medications can slow bone loss, and bone-building treatments can increase bone density. The main goal is to lower your risk of fractures. Combined with calcium, vitamin D, exercise, and fall prevention, treatment can help stabilize or improve bone density over time.
How often do I need a bone density scan?
It depends on your results and treatment. People starting or changing osteoporosis medication often have a follow-up DXA scan after one to two years, while those with normal or mildly low bone density may be retested less often. For accurate comparisons, it's best to repeat scans on the same machine whenever possible.
Should I take calcium and vitamin D supplements?
Food should come first. If your diet falls short, supplements can help you reach recommended amounts, such as 1,200 mg of calcium daily for women over 50. More isn't better: too much calcium from supplements can raise the risk of kidney stones. Your clinician can check your vitamin D level and recommend the right dose for you.
Are osteoporosis medications safe?
Most people tolerate them well. Rare but serious side effects, such as osteonecrosis of the jaw and unusual thigh bone fractures, have been linked to long-term use of some medicines. For people at high risk of fracture, the benefit of preventing broken bones generally outweighs these risks. Your endocrinologist will review your history, dental health, and kidney function before choosing treatment.
Can men get osteoporosis?
Yes. According to the Bone Health & Osteoporosis Foundation, up to one in four men age 50 and older will break a bone due to osteoporosis. Men are more likely to have a secondary cause, such as low testosterone, long-term steroid use, or heavy alcohol use, so an endocrine evaluation can be especially helpful.
Sources & further reading
- Bone Health & Osteoporosis Foundation: What Is Osteoporosis?
- Bone Health & Osteoporosis Foundation: Bone Density Testing
- Bone Health & Osteoporosis Foundation: Calcium and Vitamin D
- U.S. Preventive Services Task Force: Osteoporosis Screening
- NIAMS: Osteoporosis
Last reviewed September 19, 2026. This page is educational and is not a substitute for personal medical advice — see our medical disclaimer.
